The number of Anaplasmosis infections reported around the world have been steadily increasing since the first reported case of in 1990. Ticks carrying Anaplasma phagocytophilum have been identified in North America, Europe, and Asia, with the highest incidence in North America.

Bartonellosis is a group of infectious diseases caused by bacteria within the Bartonella genus. The bacteria are fastidious, aerobic, gram-negative cocci/small rods, and are hemotropic. The bacteria invade erythrocytes and the lining of blood vessels where they then proliferate.

Blastomycosis is an infection caused by the fungus Blastomyces dermatitidis. This fungus exists in mold form in the environment; it produces microscopic fungal spores, particularly in moist soil and in decomposing matter such as wood and leaves.

Brucellosis occurs commonly in areas without effective public health and domestic animal health programs. The areas with the highest risk include the Mediterranean area, Eastern Europe, Africa, the Middle East, Asia, Mexico, and South and Central America. The biggest risk comes from consuming unpasteurized milk and milk products, which tends to be more common outside of the U.S.A but is also becoming more common all over North America as well.

The first case of Candida auris was reported in 2009 in Japan in the ear of an infected patient. Since then, it has been reported in at least 30 countries on six continents.

In Canada, the first known case of multidrug-resistant Candida auris was reported in July 2017 in an individual who had a two-year history of recurrent ear complaints after a trip to India that included hospitalization for a brain abscess following oral surgery.

There is a range of COVID-19 disease severity, ranging from asymptomatic or mild, to moderate, severe and critical disease. The most commonly observed symptoms of COVID-19 infection are fever, flu, fatigue, new or worsening cough, loss of appetite, loss of smell and/or taste, muscle and body ache, and headache.

Ebola Virus Disease (EVD) is caused by a virus within the genus Ebolavirus. Four strains of the virus (Ebola, Sudan, Taï Forest, and Bundibugyo) have been known to cause EVD in humans. The disease is rare and deadly, most commonly affecting people and nonhuman primates (monkeys, gorillas, and chimpanzees).

Enterovirus D68 (EV- D68) shares biologic and epidemiologic features with human rhinoviruses (HRV). They are a species within the Enterovirus genus of the Picornaviridae family. Approximately 100 serotypes of nonpolio enteroviruses have been recognized; EV-D68 (identified in 1962) has been one of the less commonly identified and reported.

Type B Tularemia is found throughout North America and continental Europe, Russia, China and Japan. This disease is present during all months of the year. However, there is a higher prevalence in early winter (during rabbit hunting season) and the summer (when ticks and deerflies are abundant). Yearly, the number of cases show variation which may be due to temperature and precipitation.

Enterovirus D68 (EV- D68) shares biologic and epidemiologic features with human rhinoviruses (HRV). They are a species within the Enterovirus genus of the Picornaviridae family. Approximately 100 serotypes of nonpolio enteroviruses have been recognized; EV-D68 (identified in 1962) has been one of the less commonly identified and reported.

Type B Tularemia is found throughout North America and continental Europe, Russia, China and Japan. This disease is present during all months of the year. However, there is a higher prevalence in early winter (during rabbit hunting season) and the summer (when ticks and deerflies are abundant). Yearly, the number of cases show variation which may be due to temperature and precipitation.

Ignatzschineria indica (I. indica) infection is caused by myiasis, the infection of human tissue by fly larvae. It is transmitted by the larvae (maggots) of flesh flies (Sarcophaginae) and blow flies (Calliphoridae).

Legionellosis is caused by Legionella species, small, gram-negative, aerobic bacilli that are found in natural and man-made environments such as cooling towers, potable water systems, lakes, rivers, and streams. Legionella spp. can also be found in soil. Since 1977, 60 different Legionella species have been described to date, with 26 of them having been linked to disease in humans.

Lyme disease is a bacterial infection caused by Borrelia burgdorferi. It spread through the bite of infected ticks. Ticks attach to any part of the human body but are often found in hard-to-see areas. In most cases, the tick must be attached for at least 24 hours before Lyme disease can be transmitted.

In November 2015, a report from China first described plasmid-mediated colistin-resistance caused by the mcr-1 gene. Following that report, retrospective investigations of historical isolates have identified the rare occurrence of mcr-1 in Enterobacteriaceae from the 1980s. Bacteria with this resistance mechanism have now been identified from humans, food, environmental samples, and food animals in at least 20 countries around the world.

Measles is still prevalent throughout the world especially in many developing nations, including different parts of Africa and Asia. According to WHO, measles is a leading cause of vaccine-preventable deaths in children worldwide. The majority (more than 95%) of measles deaths occur in countries with low per capita incomes and weak health infrastructures.

Middle East respiratory syndrome (MERS) is a viral respiratory illness that is new to humans, caused by a novel coronavirus (MERS-CoV).

Coronaviruses are a large family of viruses, common throughout the world. They can infect humans and animals. In humans, coronaviruses usually cause mild to moderate upper-respiratory illness, but some can cause severe illness such as the one that caused SARS in 2003.

The mumps infection is caused by the mumps virus, an enveloped, negative-sense, single-stranded RNA virus which belongs to the Rubulavirus genus in the Paramyxoviridae family. Typically, fever, headache, malaise and muscle aches are followed by characteristic painful swelling (inflammation) of the parotid (salivary) gland on one (more common) or both sides of the face.

Mycoplasma genitalium (M. genitalium, or Mgen) is a small facultative anaerobic bacterium and a risk group 2 pathogen. M. genitalium is sexually transmitted through direct mucosal contact. Infections can be asymptomatic or symptomatic, and evidence has suggested persistent infections do occur.

Noroviruses are a cause of the majority of acute gastroenteritis in humans. They are the leading cause of acute gastroenteritis in all age groups and the leading cause of severe acute gastroenteritis among children less than 5 years of age. In addition, they are the leading cause of food-borne illness and the leading cause of illness and outbreaks from contaminated food.

Pertussis, whooping cough, is a contagious infection of the lungs and airways is caused by the bacterium Bordetella pertussis, a small, fastidious, Gram-negative, coccobacilli.  Bordetella pertussis attaches to the cilia that line the upper respiratory tract and releases toxins that damage it and cause the airways to swell. Pertussis is primarily a toxin-mediated disease. Chronic carriers of B. pertussis are uncommon.

Powassan disease cases are rare, but infections are endemic in the upper Midwest of the United States, Canada, and far-eastern Russia. It is the only tick-borne virus to be endemic in North America. The cases occur primarily in the late spring, early summer, and mid-fall when ticks are most active due to the warmer weather.

Respiratory Syncytial Virus (RSV) is a very common virus that causes infections of the respiratory tract. It is an enveloped, negative-sense, single-stranded RNA virus that belongs to the Orthopneumovirus genus in the Paramyxoviridae family. Two subtypes of RSV have been identified: RSV/A and RSV/B. Subtype A is more prevalent than subtype B.

Syphilis is a sexually transmitted bacterial disease caused by bacterium Treponema pallidum subspecies pallidum.  The strain T. pallidum subsp. pallidum causes venereal syphilis; T. pallidum subsp. endemicum causes endemic syphilis (bejel); T. pallidum subsp. pertenue causes yaws and T. carateum causes pinta.

West Nile virus (WNV) is a mosquito-borne disease (MBD) caused by a positive, single-stranded RNA virus belonging to the genus Flavivirus, in the Flaviviridae family. MNV is found in Africa, Europe, the Middle East, West Asia, and North America, including Canada.