Interventions to Prevent HIV Transmission in Serodiscordant Couples

Publication Summary

The purpose of this paper is to review the literature for prevention interventions that target either men who have sex with men (MSM) or heterosexual discordant couples.


  • HIV-negative partners of PHAs are at risk of HIV acquisition.
  • Several reviews conclude that condom interventions among discordant couples prevent HIV transmission.
  • HIV testing with counselling and support is effective in preventing HIV among discordant couples and should be promoted as a major prevention strategy.
  • Some early research suggests that HIV transmission rates are reduced when PHAs are on HAART with “complete” viral suppression.